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C. elegans has one gene encoding an IP 3 receptor, itr - 1 . Worms homozygous for the null allele of the IP 3 receptor, itr - 1 (n2559) are sterile [ 11 ]. ......

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Download to citation manager. Citing Articles. Right arrow ... functions primarily to generate IP3 that controls ITR - 1 activity. In contrast, IP3 generated ......

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(A) A gain-of-function allele of itr - 1 , sy290, is epistatic over the partial loss-of-function plc- 1 (tm753) allele, rescuing the embryonic lethality to the ......

Download to citation manager. Right arrow, reprints & permissions ... IP3Rs in C. elegans are encoded by a single gene, itr - 1 , and are widely expressed. ......

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20 itr - 1 animals for normalized pharyngeal pumping rates. ... You may download the image(s) above for non-profit educational presentation use only, ......

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